- Gianna Crane (2006-2007, 2008)
Lila Rae Alcazar is born on October 24, 2006 to Skye Chandler Quartermaine and Lorenzo Alcazar. During her pregnancy, Skye fears having a gangster's child, and flees town with the help of Robert Scorpio. Close to her due date, Skye calls her adoptive grandfather, Edward Quartermaine, and the call is traced by Alcazar. He finds his way to Skye, but is tied to a chair by Robert and Luke Spencer. Skye goes into labor, and Luke unties Alcazar. Skye returns to Port Charles, and she and Alcazar soon reconcile. Lila's last name is changed to Alcazar, but months later Alcazar is murdered. Over a period of time, Skye chooses to take Lila and leave Port Charles, to start over elsewhere.
- Caden and Nicholas Laughlin (2006)
- Nathan and Spencer Casamassima (2006-2007)
- Lance Doven (2008)
- Rami Yousef (2009)
- Davin Ransom (August 13, 2009-present)
Spencer Alexei Nikolaevich Cassadine (born as John Michael Jacks) is born in February 2006 to Jasper Jacks and Courtney Matthews. On Courtney's deathbed, Jax reveals to Courtney that Nikolas Cassadine is the baby's biological father. Jax chooses to keep the secret and raise the baby as his own. Naming the baby John Jacks in honor of his late father, Jax soon discovers that Carly Corinthos has learned the truth. Carly agrees to keep Jax's secret, and offers to help raise baby John. Robin Scorpio also learns of the child's true paternity, and during the baby's christening ceremony, reveals the truth to Nikolas.
Returned to his father, baby John's name is changed to Spencer Cassadine in an effort to show the conclusion of the Cassadine/Spencer feud as well as admit his ties to that family via half siblings Lucky and Lulu as well as stepfather Luke.
The child's great grandmother, Helena hires Colleen McHenry to become the baby's nanny. Colleen soon develops an unrequited crush on Nikolas, and becomes desperate for the two of them and Spencer to become a family. Under disguise, Colleen kidnaps Spencer from a manger on Christmas Eve, and changes his name. Nikolas and Emily Quartermaine travel to Moscow and find Helena christening him with a traditional Cassadine name. Helena holds a knife to Spencer, but Emily punches her and takes the baby. Helena escapes while they wait for authorities. Spencer returns to town with Nikolas and Emily where a party is thrown for him.
When Nikolas begins spending time with Nadine Crowell, Spencer introduces Nadine to their horses, and helps when Nadine and Nikolas put together his train set.
Michael Corinthos IIIEdit
- Main article: Michael Corinthos
- Blake and Dylan Hopkins (1998-2001)
- Tiarnan Cunningham (2001-2002)
- Dylan Cash (2002-2008)
- Drew Garrett (2009-)
Michael Morgan Corinthos III (previously Michael Morgan & Michael Alan Quartermaine') is the son of the late A.J. Quartermaine and Carly Corinthos. Carly originally tries to pass Michael off as the son of Tony Jones, and later Jason Morgan. However, Jason's girlfriend Robin Scorpio discovers the truth and ultimately tells A.J. Michael is later adopted by Carly's on-again, off-again husband, Mob boss Sonny Corinthos. Michael is left in a coma after being shot in the head in April 2008. Michael emerges from his coma after brain surgery performed by Patrick Drake in May 2009.
- Main article: Morgan Corinthos
- Adonios and Isador Talamo (2003-2004)
- Dylan and Jordan Cline (2004-2005)
- Jake Simms (2005) 
- George Juarez (2005-2009) 
- Aaron Refvem (May 2009-) 
Shortly after Michael's shooting, Carly asks Sonny to sign away his rights to both Morgan and a comatose Michael. Sonny refuses, and Carly decides to take Morgan and go on the run from Sonny, until Jason agrees to take over Sonny's business provided he sign away his rights; Sonny painfully decides that signing away his rights is the best thing to do. He attends a private Catholic school, Queen of Angels.
Recently, Carly has allowed Sonny back into her son's life. When Sonny, Carly, and Jason are trapped in the burning General Hospital, Diane Miller reveals to Alexis Davis that Morgan stands to be the wealthiest minor in New York should the three of them not survive. After Carly survives the ordeal, Morgan is happily shocked to learn that she has reunited with Jasper Jacks, and that he will be moving back in.
Morgan has begun to develop a close bond with his half-brother, Dante Falconeri, however he is unaware of their true relation. Morgan looks up to Dante as an older brother figure after Dante protects Morgan against Kristina's boyfriend, Keifer, who was harassing him for information on Kristina's where-abouts. Ever since they have bonded, as Morgan reminds Dante of his childhood self. In September 2009, during Edward's accident at the local carnival, Morgan is almost hit by Edward's car when Dante pushes him out of the way. Morgan is fine, however Dante suffers major internal bleeding, but is expected to recover. Morgan gives Dante his Yankee bating helmet he won at the carnival as a thank-you for saving his life and proposes to Carly that Dante move in with them when he is recovering.
Overall, Morgan is a quiet, gentle, helpful boy. When he is provoked or in danger, Morgan retains a cool head and uses his wit and smarts to get himself out of situations. He is an extreme sports fan, especially baseball (his favorite team is the Yankees). Since Michael's accident he has grown just a bit worrisome, especially where his mother Carly is concerned.
On October 29, 2009; Morgan became the big brother to Josslyn Jacks.
- Main article: Kristina Davis
- Unknown actresses (December 2002 - July 2003)
- Kara and Shelby Hoffman (July 23, 2003-December 19, 2003 )
- Emma and Sarah Smith (December 23, 2003-November 11, 2005)
- Kali Rodriguez (November 15, 2005- August 13, 2008)
- Lexi Ainsworth (June 24, 2009-present)
Kristina Adela Corinthos-Davis (formerly Ashton) is the daughter of Sonny Corinthos and Alexis Davis. Having been recently aged from 6 to 16 in June, the now high schooler Kristina didn't hesitate to stir things up in Port Charles right away.
Emma Scorpio DrakeEdit
- Ruby and Rose Romero (November 4, 2008-February 18, 2009)
- Gianna and Jessie (March 3, 2009-present)
Emma Grace Scorpio Drake is the daughter of Patrick Drake and Robin Scorpio. Emma was conceived on December 23, 2007, when a grief stricken Robin went to Patrick's apartment for comfort following the funeral of her cousin, Georgie. The couple had recently broken up. Robin's due date should of been 9/14/2008 but she was pregnant for 46 and half weeks pregnant 10 months.
On January 21, 2008, Robin is informed by Dr. Kelly Lee that she is pregnant. Up until that point, Robin had been planning to be artificially inseminated using a sperm donor. At first, Robin decides not to tell Patrick that he is the father of their child because Patrick had always declared he did not want to be a father, which in fact was the cause of their most recent break-up. On February 29, Patrick confronts Robin with the truth knowing that he is the father of her unborn child, which Robin confirms. The newly reconciled and happy couple get an ultrasound which shows that they are expecting a daughter on November 12, 2008.
On October 31, 2008, Robin goes into labor during her wedding to Patrick. After a few brief scares, Emma is delivered via C-section happy and healthy on November 3. She has a cut on her ear, however, and her parents become very concerned because Robin is HIV-positive, and they fear that Emma could have been exposed. However, test results later prove that she is HIV-negative.
As of yet, no official godparents have been picked, although Robin has asked Spinelli to be Emma's honorary uncle. Patrick and Robin do eventually marry, but without Emma in attendance. In February 2009, when Emma comes down with a fever she is left in the care of an alarmed Maxie. With Johnny Zacchara's help, Maxie brings Emma to the hospital where she is diagnosed with pneumonia. Emma is later cured by the "power of a mother's love".
On April 3, 2009, Robin imagines seeing an older Emma on the waterfront due to Robin's post-partum depression.
- McKenna & Karleigh (November 2009-)
Josslyn John Jacks is the daughter of Carly and Jasper Jacks. She is the younger sister of Michael and Morgan Corinthos. She is the first granddaughter of Bobbie Spencer and Jane Jacks. Her Godfather is Jason Morgan.
In April, Kelly Lee tells Carly she is pregnant and tells her that it is a very high risk pregnancy. Carly is supposed to avoid stress. The baby is due in November 2009. On October 29, 2009, Carly was kidnapped by Claudia Corinthos and went into labor and with Claudia's help, gave birth to Josslyn in a cabin soon after. But as Claudia tried to steal Josslyn, Carly's son and Josslyn's brother Michael came in and killed Claudia. 
- Hope and Faith Dever (2005-2007)
- Iris and Ivy Kaim (April 9, 2007-January 4, 2008)
- Haley Alexis Pullos (July 2, 2009-)
On November 10, 2005, Molly is born on-screen in the Glencoe tunnel after many of Port Charles' most well-known residents are involved in a train crash. Following her parents' divorce, Ric wins primary custody of Molly, with Alexis having visitation. Both Ric and Alexis later settle on joint custody.
A SORASed Molly appears on July 2, 2009, and is shown to be good friends with her cousin, Morgan Corinthos. She is an excellent scholar with a good pitching arm, a combination which she uses during the 2009 hospital carnival to cause all the "Dunk-a-Hunks" to fall into the water.
- Edward and James Nigbor (2007-2008)
- James Nigbor (2009)
Jacob Martin "Jake" Spencer is the son of Jason Morgan and Elizabeth Webber, and the legal son of Lucky Spencer. After catching her husband Lucky Spencer in bed with Maxie Jones, Elizabeth runs to Jason. A short time later, Elizabeth learns that she is pregnant, and has a paternity test done. After receiving the test results, Elizabeth keeps the father's identity a secret, and lets everyone believe that Lucky is the father. Shortly after being held hostage with most of Port Charles, Elizabeth tells Jason the truth while they are stuck in an elevator. Elizabeth asks Jason to let everyone continue to believe that Lucky is the father to ensure the baby's safety from Jason's enemies. Months later, Elizabeth gives birth to a baby boy, naming him Jacob Martin Spencer (with Jason's initials "JM") in May 2007.
Jake is soon kidnapped from the park while Elizabeth has her back turned. The kidnapping was witnessed by Sam McCall. Jason, who had recently murdered Lorenzo Alcazar, is anxious to go free in order to find his son. After Jason is released on bail, Amelia Joffe has a phone conversation with a woman named Maureen Harper. During the phone call, Amelia hears a newborn baby crying in the background, and knowing that Maureen's baby had died in a house fire, realizes that Maureen is baby Jake's kidnapper. Jason and Amelia drive to Maureen's home, where they learn that the baby was indeed Jake. Maureen hands the baby over, and reveals that Sam witnessed the kidnapping. Upon returning to Port Charles, Jason reunites Elizabeth with her son before he is arrested for jumping bail.
During the Black and White Ball at Wyndemere Castle, Lucky and Elizabeth get into a heated argument. Jason comes in and finally admits the truth. He states that he is Jake's father and Elizabeth confirms it, much to Lucky's dismay. Jason and Elizabeth decide that it is best to continue their charade, and Lucky agrees to continue being Jake's father.
Jake is again kidnapped by Jason's enemies, and is rescued by Jason and Sam.
In September 2009, Jake is buried under a tent during the chaos at the carnival and is rushed to the hospital, but has no serious injuries.
- Unknown Babies #1 (2004)
- Unknown Babies #2 (2004)
- Ashwyn Bagga (2004-2006)
- Braeden Walkes (2006-present)
Cameron Webber is the son of Zander Smith and Elizabeth Webber. Having slept with Zander in October 2003 while still married to Ric Lansing, Elizabeth learns that she is pregnant. Ric and Elizabeth agreed to raise the baby together as Ric's but as their marriage falls apart, she chooses to leave town to have the baby. Elizabeth returns on June 18, 2004, with her baby, naming him Cameron after his late grandfather, Cameron Lewis.
Elizabeth soon reunites with Lucky Spencer, who becomes Cameron's stepfather.
On January 11, 2008, a misbehaving Cameron plays with matches. Liz repeatedly tells Cameron to leave the matches alone, but he disobeys her orders. After throwing a lit match into the trash can, Liz chases Cam outside. The trash can catches fire, while Liz and Cam are locked outside. Liz busts through a window and saves her other baby, Jake Spencer. After renovations are complete, Liz and her children move back in.
- ↑ GH recap 2/20/06 - abc.com at the Internet Archive
- ↑ GH recap 4/4/08 - soaps.com
- ↑ General Hospital recap 5/15/09 - soaps.com
- ↑ Jake Simms as Morgan - TV.com
- ↑ George Juarez as Morgan - TV.com
- ↑ General Hospital comings and goings - soaps.com
- ↑ GH recap 10/24/03 - abc.com
- ↑ http://www.soaps.com/generalhospital/update/7431/A_lot_To_Learn_About_Family
- ↑ Alexis Pullos Joins the Cast of General Hospital as NuMolly - soaps.com
- ↑ GH recap 1/11/08 - soaps.com